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Liposomes have grown as an important biomedical carrier system. One of the most critical factors influencing the performance of liposome is particle size. High-pressure homogenization, extrusion and sonication are methods for reducing liposome size. The extrusion technique is a reasonably mild and quick procedure among them.
Liposome with double layer of phospholipid molecules. Image credits: Genizer LLC
The Genizer Jacketed Liposome Extruder utilizes a nitrogen gas cylinder to force a drug, protein or gene liposome suspension via a track-etched membrane with a predetermined pore size; generally, 5–10 passes are enough to create a sample with consistent liposome size. The Genizer Jacketed Liposome Extruders are designed to produce uniform unilamellar liposomes and lipopolyplexes with minimal dead volume.
Genizer Jacketed Liposome Extruder for Liposome Size Reduction. Image Credit: Genizer LLC
Achieve Efficient Cellular Lysis with the NanoGenizer-30K
The GJE-100ML Jacketed Liposome Extruder
The GOE-142MM, an Online Liposome Extrusion Device
The Mini HandExtruder-1 mL for Liposome Extrusion
The MixGenizer-30K for Microfluidic Mixing
The Pilotgenizer-30K - A Pilot High-Pressure Homogenizer
Use the Mini Hand Homogenizer for Small Biochemical Projects
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